Updates on the relationship between vitamin D and epilepsy
10.3760/cma.j.issn.1673-4408.2016.12.013
- VernacularTitle:维生素D与癫疒间的相关性研究进展
- Author:
Jinyan ZHAO
;
Guilian SUN
- Keywords:
Vitamin D;
Vitamin D receptor;
Epilepsy;
Antiepileptic drug
- From:
International Journal of Pediatrics
2016;43(12):948-952
- CountryChina
- Language:Chinese
-
Abstract:
Vitamin D adjusts the body′s absorption and utilization of calciumand phosphorus. Vitamin D deficiency is closely related to incidence of many disease. Several disorders,both systemic and those of the nerv-ous system,have been linked with vitamin D deficiency. Neurological disorders with a vitamin D link include but are not limited to multiple sclerosis,Alzheimer and Parkinson disease,as well as cerebrovascular disorders. In re-cent years,studies have found that the vitamin D may play a critical role in the pathogenesis of epilepsy and pos-sess certain anticonvulsant effects. This article summarized the role of vitamin D in the nervous system and epi-lepsy,the level of serum vitamin D and the correlation of the polymorphism of its receptor genes with epilepsy. The review also summarizes the interaction between antiepileptic drugs and vitamin D.
