Two autoantibody tests for diagnosis of idiopathic membranous nephropathy-Urgent call to action
10.3760/cma.j.issn.1009-9158.2016.12.001
- VernacularTitle:需尽快开展诊断特发性膜性肾病的两项检验
- Author:
Hong CHENG
;
Yipu CHEN
- Keywords:
Glomerulonephritis,membranous;
Receptors,phospholipase A2
- From:
Chinese Journal of Laboratory Medicine
2016;39(12):873-875
- CountryChina
- Language:Chinese
-
Abstract:
Over the past decade , with the rapid increase of the incidence of idiopathic membranous nephropathy (IMN) in our country, the diagnosis and treatment of IMN has been paid more and more attention.IMN is an autoimmune disease.Two important podocyte autoantigens , PLA2R and THSD7A, have been indentified sine 2009.Subsequently , serum anti-PLA2R antibody test and anti-THSD7A antibody test have also been used in clinical .Preliminary applications show that these two tests can not only help IMN diagnosis and differential diagnosis , but also help IMN prognosis.
