Influenza vaccination in patients with systemic lupus erythematosus
10.3760/cma.j.issn.1674-2397.2016.06.016
- VernacularTitle:流感疫苗在系统性红斑狼疮患者中的应用
- Author:
Chuancong WU
;
Lili DENG
;
Zhangli YANG
;
Wei LUO
;
Lihui MA
- Keywords:
Lupus erythematosus,systemic;
Influenza vaccine;
Vaccination
- From:
Chinese Journal of Clinical Infectious Diseases
2016;9(6):547-550
- CountryChina
- Language:Chinese
-
Abstract:
Patients with systemic lupus erythematosus (SLE)are susceptible to influenza virus infection due to autoimmune disorder,use of glucocorticoids and the immunosuppressive agents.Influenza virus infection affects the disease stability,and the mortality of influenza virus infection in SLE patients is 5 times higher than that in general people infected by influenza virus.Vaccination is the most effective measure to prevent influenza virus infection.There is lack of studies on the influenza immunization in SLE patients in China,so this paper reviews prevention effect and safety of inoculation,the immune response to vaccine as well as the factors influencing immune response in influenza vaccination for SLE patients.