Comparison of diagnostic value between TIRADS and ultrasound patterns of ATA (2015) guidelines in the differentiation of benign and malignant thyroid nodule
10.3760/cma.j.issn.1000-6699.2016.12.005
- VernacularTitle:TIRADS与2015年美国甲状腺学会指南超声模式对甲状腺结节良恶性鉴别诊断效能的对比研究
- Author:
Ting XU
;
Jingyu GU
;
Xinhua YE
;
Shuhang XU
;
Yang WU
;
Xinyu SHAO
;
Yuan GAO
;
Dezhen LIU
;
Weiping LU
;
Fei HUA
;
Bimin SHI
;
Jun LIANG
;
Lan XU
;
Wei TANG
;
Chao LIU
;
Xiaohong WU
- Keywords:
Thyroid nodule;
Thyroid imaging reporting and data system;
Ultrasound patterns;
2015 American Thyroid Association guidelines
- From:
Chinese Journal of Endocrinology and Metabolism
2016;32(12):999-1002
- CountryChina
- Language:Chinese
-
Abstract:
To compare the diagnostic value between the thyroid imaging reporting and data system ( TIRADS) and ultrasound ( US ) patterns of 2015 American Thyroid Association ( ATA ) guidelines in the differentiation of benign and malignant thyroid nodules. 639 patients in Jiangsu province who were scheduled for ultrasound-guided fine-needle aspiration biopsy or thyroidectomy were recruited for the retrospective study. All of them were categorized based on TIRADS and ultrasound patterns of ATA ( 2015 ) guidelines. The receiver operating characteristic curve was established to assess and compare the diagnostic value of the two models. Results:( 1 ) 639 patients with 847 thyroid nodules were included in this study, 510 females and 129 males. The mean age was (46. 77 ±12.98)yearsold. (2)818nodulescouldbeclassifiedaccordingtoTIRADS. ThemalignancyratesofTIRADS2,3, 4A, 4B, 5 were 0, 15. 9%, 49. 1%, 78. 8% ,and 100%, respectively. (3) Ultrasound patterns of ATA could be assigned to 793 nodules. The malignancy rates of nodules with very low, low, intermediate, high suspicion for malignancy were 6. 2%, 10. 3%, 24. 9% and 70. 1%, respectively. (4) Ultrasound patterns of ATA had higher specificity (77. 9%) compared to TIRADS. The sensitivity and area under curve of ultrasound patterns of ATA were lower than those of TIRADS, though, not significant. Ultrasound patterns of ATA(2015) guidelines may yield higher specificity in the differential diagnosis of benign and malignant thyroid nodules, while TIRADS classification may offer a relatively higher sensitivity and area under curve.
