Validation of LC-MS in clinical laboratory
10.3760/cma.j.issn.1009-9158.2016.12.028
- VernacularTitle:临床检验液相色谱－质谱检测方法的确认
- Author:
Yuanyuan YE
;
Wei WANG
;
Haijian ZHAO
;
Zhiguo WANG
- Keywords:
Chromatography,liquid;
Mass spectrometry;
Clinical Laboratory technirques
- From:
Chinese Journal of Laboratory Medicine
2016;39(12):991-994
- CountryChina
- Language:Chinese
-
Abstract:
Liquid Chromatography-Mass Spectrometry ( LC-MS) is becoming more and more widely used in clinical laboratory ,and LC-MS related quality management requires more rigid than it was .According to CLSI C62-A,this article provides a reference for the validation procedure of LC-MS assay, including limit of detection and lower limit of the measuring interval , linearity and dilution, imprecision, assay interferences and trueness.
