Research advances of forensically lfuid/tissues identiifcation based on DNA methylation analysis
10.13618/j.issn.1001-5728.2016.06.015
- VernacularTitle:DNA甲基化在组织/体液来源鉴定中的研究进展
- Author:
Yunshu JIA
;
Zhongwei CAO
;
Wenqiong ZHANG
;
Chao XIAO
;
Tian WEI
;
Shaohua YI
- Keywords:
forensic biological evidence;
epigenetics;
DNA methylation;
identiifcation of tissues/body lfuids
- From:
Chinese Journal of Forensic Medicine
2016;31(6):591-594
- CountryChina
- Language:Chinese
-
Abstract:
Identiifcation of tissues/body lfuids in forensic science is important for criminal cases investigation such as crime scene reconstruction, conclude the character of crime. Recently, many researches of Epigenetic shows that tissue speciifc differentially methylated regions(tDMRs) have the ability to as a biomarker for identiifcation of tissues/body lfuids. In this paper, we reviewed the study progress and summarized the probability, advantage and disadvantage as well as application value and the development direction of the application of DNA methylation in the aspect of identifying the tissues/ body lfuids source, aiming at providing a reference for the related research and application.
