Evaluation of mycobacterium tuberculosis IgG antibody protein chip in patients with active and inactive tuberculosis
10.3969/j.issn.1005-1678.2016.12.050
- VernacularTitle:结核分枝杆菌IgG抗体蛋白芯片对活动性与非活动性结核患者疗效的评价
- Author:
Neng SONG
;
Yan LIU
;
Yuanshan DUAN
;
Jie MA
- Keywords:
M.tuberculosis;
protein microarray chip;
inactive tuberculosis;
diagnosis of tuberculosis
- From:
Chinese Journal of Biochemical Pharmaceutics
2016;36(12):174-176
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore protein microarray chip diagnostic value for patients with active and inactive tuberculosis.Methods 178 cases of active patients tuberculosis and 79 cases of inactive tuberculosis patients and 92 cases of healthy control using protein microarray chip detection.Results Tuberculosis protein chip had a diagnostic value for tuberculosis and the positive rate is 58.4%; combined the diagnostic value of three kinds of proteins is higher than the diagnostic value of a single protein;16 kD protein of inactive tuberculosis positive rate was 16.4%, better than the positive rate of 3.4% for active tuberculosis (P<0.05).Conclusion Tuberculosis protein chip has a diagnostic value for active tuberculosis and inactive tuberculosis.16 kD protein positive rate more than 38 kD protein in patients with inactive tuberculosis (P<0.05).
