Fundus autofluorescence and its applications in retinal diseases
10.3760/cma.j.issn.1005-1015.2017.01.027
- VernacularTitle:临床常见眼底疾病眼底自身荧光特征及其意义研究现状
- Author:
Ruoan HAN
;
Youxin CHEN
- Keywords:
Fluorescence;
Retinal diseases/diagnosis;
Diagnostic imaging;
Review
- From:
Chinese Journal of Ocular Fundus Diseases
2017;33(1):83-86
- CountryChina
- Language:Chinese
-
Abstract:
Autofluorescence is produced by lipofuscin in retinal pigment epithelium (RPE) cells which is induced by exciting light and enables the visualization of lipofuscin changes in the RPE cells, thus showing the function of RPE and photoreceptor cells. Fundus autofluorescence (FAF) imaging is a non-invasive imaging technique providing information of RPE and photoreceptor cells, which is not obtainable with other imaging modalities. The scope of applications includes identification of diseased RPE in retinal diseases, elucidating pathophysiological mechanisms, estimating disease progression and prognosis, guiding treatment protocols. Common fundus diseases have different pathological types, levels and causes, so they can cause various damages of RPE and photoreceptor cells which induce complicated FAF. It is worth further observing and investigating the common retinal diseases' FAF characteristics and clinical applications.
