Study of correlation between biochemical markers of bone metabolism and postmenopausal osteoporotic vertebral fractures
10.3969/j.issn.1671-8348.2017.01.009
- VernacularTitle:骨代谢生化指标与绝经后骨质疏松性腰椎骨折相关性分析
- Author:
Shaochuan HUO
;
Lujue DONG
;
Hongyu TANG
;
Yong LIU
;
Hai GUO
;
Jianfa CHEN
;
Zhangrong DENG
;
Delong CHEN
;
Haibin WANG
- Keywords:
osteoporosis,postmenopausal;
postmenopause;
bone density;
bone and bones;
postmenopausal osteoporotic;
ver-tebral fractures
- From:
Chongqing Medicine
2017;46(1):48-50
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study correlation between biochemical markers of bone metabolism and postmenopausal osteoporot-ic vertebral fractures.Methods The clinical data of 100 cases with postmenopausal osteoporotic were study retrospectively.Fifty patients were postmenopausal osteoporotic,the rests were postmenopausal osteoporotic vertebral fractures.Lumbar spine,hip BMD,serum P1NP,β-CTX,N-MID,25-(OH)VitD and Ca2 + were recorded.Results There was a significant difference among ser-um P1NP,β-CTX and 25-(OH)VitD(P <0.05 ).There was positive correlation between postmenopausal osteoporotic vertebral fracture with serum P1NP (P <0.05),and negative correlation with serum 25-(OH)VitD (P <0.05),but had no correlation with serumβ-CTX (P >0.05).Conclusion Serum P1NP and 25-(OH)VitD could predict risk of postmenopausal osteoporotic vertebral fractures.Biochemical markers of bone metabolism combined with BMD could reduce postmenopausal osteoporosis fractures.
