Research progress of microRNA in the development of the pancreas and type 1 diabetes
10.3969/j.issn.1006-6187.2017.01.019
- VernacularTitle:microRNA在胰腺发育及1型糖尿病中的研究进展
- Author:
Guofeng WANG
;
Tao YANG
- Keywords:
MicroRNAs;
Diabetes mellituse,type 1;
Pancreas development;
Research progress
- From:
Chinese Journal of Diabetes
2017;25(1):85-87
- CountryChina
- Language:Chinese
-
Abstract:
[Summary] The pathogenesis of type 1 diabetes has not been thoroughly understood. MicroRNA is a kind of small molecule RNA in regulating gene expression at post-transcriptional level. The dysfunction and amount changes of microRNA involve in the regulation of pancreaticβcell volume and function,and thus are related to type 1 diabetes. Here,we reviewed the research advances of microRNA in the development of the pancreas,insulin secretion and type 1 diabetes.
