Investigation and analysis of pathogens distribution and infective routes for ventilator associated pneumonia
10.3969/J.ISSN.1672-8270.2017.01.012
- VernacularTitle:呼吸机相关性肺炎的感染途径及病原菌分布调查分析
- Author:
Shuai WANG
;
Lizhan AN
- Keywords:
Ventilator associated pneumonia;
Infective routes;
Nosocomial infection
- From:
China Medical Equipment
2017;14(1):35-38
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the infective routes and the pathogen type distribution of ventilator associated pneumonia (VAP).Methods: 183 ventilator associated pneumonia patients (75 cases were early-onset VAP and 108 cases were late-onset VAP, and the different point was whether machine had been used 72 h) who once were treated in intensive care unit(ICU)during the term of January 2013 and December 2015 were researched in this paper. To collect samples from phlegm in lower respiratory tract, secrete of oropharynx, air sac of tracheal catheter, stomach juices, ventilator channel and condensate water, and identify pathogens and detect drug allergy. To compare the difference of pathogens distribution and infective routes between early-onset VAP and late-onset VAP by comparing identified result of the same case.Results: In 294 strains bacteria collected from different collective points, 71.09% was gram-negative bacteria, 21.09% was gram positive bacteria, 7.82% was fungus, and 129 strains were multiple-resistant bacteria. Gram-negative bacteria and gram positive bacteria in late-onset VAP patients were less than early-onset VAP patients, but the fungus was more than them, and the difference was statistically significant (x2=14.193, P=0.001); besides, the stains of multiple-resistant bacteria of late-onset patients were more than others, and the difference also was statistically significant (x2=26.375, P=0.000). Most of infection of VAP were original from stomach juices and tracheal catheter air sac, both of them were 59.77%. Most of early-onset VAP were infected by stomach juices and secrete of oropharynx, and most of late-onset VAP were infected by tracheal catheter air sac, ventilator channel and condensate water(x2=31.450,P= 0.000).Conclusion: The clinical prevention and cure for VAP should adopt comprehensive measures which depend on the aeration time of machine because there are some differences on pathogens distribution and infective routes between late-onset VAP and early-onset VAP. This research provide a evidence for efficiently prevent the occurrence and development of VAP in hospital.
