Analysis of Anxiety and Depression in Chronic Gastritis Patients
10.3969/j.issn.1008-7125.2017.02.009
- VernacularTitle:慢性胃炎患者焦虑、抑郁状态分析
- Author:
Yan ZHANG
;
Tingting ZHU
;
Qianqian XU
;
Yingchun DOU
;
Qing LI
;
Xinying MENG
;
Changhong ZHOU
- Keywords:
Gastritis;
Anxiety;
Depression;
Digestive Symptoms;
Inflammation;
Helicobacter pylori
- From:
Chinese Journal of Gastroenterology
2017;22(2):103-105
- CountryChina
- Language:Chinese
-
Abstract:
Chronic gastritis has varied clinical symptoms and prolonged course,and seriously affects the life quality of patients.Studies have shown that mood disorders might affect the pathogenesis of chronic gastritis.Aims:To investigate the incidence of anxiety and depression and its relationship with digestive symptoms,Helicobacter pylori (Hp) infection,degree and activity of inflammation in patients with chronic gastritis.Methods:A total of 235 patients with chronic non-atrophic gastritis were enrolled.Anxiety,depression,gastrointestinal symptoms,gastric mucosal inflammation and activity were evaluated,and infection of Hp was detected.Results:In the 235 patients,144 (61.3%)were accompanied by anxiety and/or depression:108 patients (46.0%)were accompanied by anxiety,129 patients (54.9%) were accompanied by depression,93 patients (39.6%)were accompanied by anxiety and depression.Incidence of abdominal pain,abdominal distention and early satiety,scores of digestive symptoms,positive rate of Hp infection and incidence of severe inflammation in patients accompanied by anxiety and/or depression were significantly higher than those in patients without anxiety and depression (P<0.05 ),but no significant difference in inflammation activity was seen between the two groups (P>0.05).Conclusions:Incidence of anxiety and depression in patients with chronic gastritis is high.Anxiety and depression are associated with abdominal pain,abdominal distention and early satiety,and can affect the inflammatory degree of gastric mucosa.Patients with anxiety and depression are susceptible to Hp infection.