Clearance effect of milk containing anti-Helicobacter pylori specific antibody:a randomized clinical trial
10.3969/j.issn.1000-484X.2017.02.023
- VernacularTitle:含幽门螺杆菌特异性抗体牛奶清除幽门螺杆菌效果的临床随机试验
- Author:
Lianmei ZHAO
;
Sisi WEI
;
Yipeng WU
;
Weihua LIU
;
Chuan ZHAO
;
Dailun HU
;
Shengmian LI
;
Xian WANG
;
Baoen SHAN
- Keywords:
Helicobacter pylori;
Antibody milk;
Randomized clinical trial
- From:
Chinese Journal of Immunology
2017;33(2):274-277
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To compare and observe the different clearance effect of milk containing anti-Helicobacter pylori specific antibody. Methods:Four H. pylori strains were used to immune dairy cows to obtain milk containing anti-Helicobacter pylori specific antibody,of which,one was standardized strain and the other three were locally epidemic. Totally 148 people were screended,in which 72 were C-14 urea breath test positive, finally 39 meet the criteria. They were divided into two groups, the test group contained 21 subjects,were treated milk containing anti-Helicobacter pylori specific antibody;the 18 subjects in control group with common milk. The study was continued for 2 months. Results:Conducting the C-14 urea breath test,9 subjects in test group were negative,but no one was changed in control group. The effective clearance rate of the test group was 42. 86%,and there was no effective clearance in the control group,so there was significant difference in the two groups(P=0. 005,P<0. 05). Conclusion: The milk containing anti-Helicobacter pylori specific antibody is polyclonal and has higher valence,and could clear H . Pylori effectively.
