Advance on the pharmacological research of dioscin
10.3969/j.issn.1001-1978.2017.02.004
- VernacularTitle:薯蓣皂苷现代药理学研究进展
- Author:
Shurong WANG
;
Shuang LING
;
Qingguang ZHANG
;
Jinwen XU
- Keywords:
dioscin;
anti-cancer;
cardiovascular disease;
liver fibrosis;
ischemia/reperfusion injury;
osteoporosis;
anti-inflam-mation
- From:
Chinese Pharmacological Bulletin
2017;33(2):161-166
- CountryChina
- Language:Chinese
-
Abstract:
Dioscin is the main ingredient of Dioscorea,a tradi-tional medical herb.Traditional theory of Chinese medicine be-lieves that Dioscorea has effects of clearing lung,digesting food, diuresis, improving blood circulation, relaxing muscles and stopping attack of malaria.Pharmacological studies have shown that dioscin has many pharmacological effects,particularly the anti-tumor effect.Many studies have also shown dioscin im-proves symptoms of atherosclerosis and protects blood vessel en-dothelium,reduces ischemia-reperfusion injury of heart,brain and kidney,lowers blood sugar,inhibits hepatic fibrosis,im-proves menopausal osteoporosis,relieves rheumatoid arthritis, ulcerative colitis and other inflammatory disorders,and posses-ses anti-bacterial and anti-viral activity.This article focuses on the progress of the modern pharmacological study of dioscin,and reports its advances in recent years.
