Low ankle-brachial index predicts cerebral microbleeds in patients with ischemic stroke
10.16571/j.cnki.1008-8199.2017.01.012
- VernacularTitle:踝肱指数和急性脑梗死患者脑微出血的相关性研究
- Author:
Chuanyou LI
;
Jing XIAO
;
Caixia DING
;
Yinyan TANG
;
Xuemei JIANG
;
Yujia ZHU
;
Dan HU
;
Lankun ZHANG
;
Han JIANG
;
Lei SHENG
- Keywords:
Ankle-brachial index;
Ischemic stroke;
Cerebral microbleeds
- From:
Journal of Medical Postgraduates
2017;30(1):57-60
- CountryChina
- Language:Chinese
-
Abstract:
Objective The abnormal ankle-brachial index ( ABI) is associated with the incidence of cardiocerebral vascular diseases, but little is known about its relationship with cerebral microbleeds (CMB).This study aimed to investigate the correlation be-tween ABI≤0.9 and different distribution patterns of CMB . Methods We enrolled 187 patients with acute lacunar infarction , inclu-ding 115 non-CMB cases and 72 CMB cases (20 strictly lobar, 24 strictly deep, and 28 lobar and deep).We analyzed the differences between the two groups and the association of abnormal ABI with the occurrence and distribution of CMB by logistic regression analysis . Results ABI≤0.9 was found in 57 (30.5%) of the patients, with a significantly higher incidence rate in the CMB group than in the non-CMB group (43.1%vs 22.6%, P=0.003).The level of ABI was negatively correlated with the number of CMBs (r=-0.211, P=0.006).Multivariate logistic regression analysis after adjusted for confounders indicated that ABI ≤0.9 was significantly associated with the presence of CMB (OR=2.363;95%CI:1.181-4.729), deep CMB (OR=3.434;95%CI:1.283-9.187), and lobar and deep CMB ( OR=2.837;95%CI:1.098-7.333) in patients with ischemic cerebrovascular disease . Conclusion Decreased ABI is a risk factor of CMB, particularly deep CMB, in patients with ischemic stroke.
