Research progress of microRNA-214 in the cervical cancer
10.16571/j.cnki.1008-8199.2017.01.022
- VernacularTitle:微小 RNA-214在宫颈癌中的研究进展
- Author:
Yu ZHANG
;
Hongying YANG
;
Yufeng YAO
;
Chuanyin LI
- Keywords:
Cervical cancer;
miR-214;
Abnormal expression
- From:
Journal of Medical Postgraduates
2017;30(1):104-107
- CountryChina
- Language:Chinese
-
Abstract:
MicroRNAs ( miRNAs ) play important roles in the processes of the occurrence and development of cancers , through regulating tumor related gene expression at post-transcription.It has shown that the expression of miR-214 is aberrant in cervi-cal cancer.Also,miR-214 could affect the proliferation, migration, invasion and apoptosis of tumor cells by targeting various genes . This article focuses on the studies of miR-214 function in cervical cancer , and will provide a novel approach for the clinical diagnosis and the treatment of cervical cancer .
