Development of the cross sign of olivepontocerebellar atrophy and its diagnostic value

VernacularTitle:橄榄脑桥小脑萎缩十字征的演变及诊断价值
Author: Shuying LI ; Liying YAO ; Ding YAO ; Yanchun LUO
Keywords: Olivopontocerebellar atrophy; Magnetic resonance imaging; Cross sign; Multi -system atrophy
From: Chinese Journal of Primary Medicine and Pharmacy 2017;24(4):547-549
CountryChina
Language:Chinese
Abstract: Objective To explore the development of the cross sign of olivepontocerebellar atrophy(OPCA) and its diagnostic value.Methods The clinical and imaging data of 8 patients with OPCA were analyzed retrospec-tively.MRI imaging used SE sequence,plain T1 WI,T2 WI,axial,coronal,sagittal imaging.Results All patients were hide onset.The major clinical presentation was cerebellar atsxia and autonomic nerve dysfunction.Positive radiographic findings were consistent with clinical presentation,mainly for the brain stem atrophy,8 patients of the group had this performance,followed by cerebellar atrophy,6 patients had symmetrical atrophy and 2 patients had asymmetric atro-phy.6 patients after onset of 1.5 -3 years showed a typical cross.Conclusion The cross sign gradually appears at a certain stage of development,and it has high specificity.So the combination of clinical and MRI is valuable for the diagnosis and differential diagnosis of OPCA.