The application value of HR -HPV detection combined with TCT in the screening of cervical cancer and pre-cancerous lesions

VernacularTitle:人高危型乳头瘤病毒检测联合液基薄层细胞学在宫颈癌和癌前病变筛查中的应用价值
Author: Ke ZHANG ; Xiaomei LUO ; Shuangling TANG
Keywords: Human papillomavirus; Thinprep cytology test; Uterine cervical neoplasms; Precancerous conditions; Multiphasic screening
From: Chinese Journal of Primary Medicine and Pharmacy 2017;24(4):589-592
CountryChina
Language:Chinese
Abstract: Objective To explore the diagnostic value of HR -HPV combined with TCT in the diagnosis of cervical cancer and precancerous lesion.Methods 1 198 cervical specimens were selected for the study.The results of HR -HPV detection and TCT detection were analyzed,with the pathological results as the gold standard,the diag-nostic value of HR -HPV and TCT in the diagnosis of cervical cancer and precancerous lesion were discussed. Results With increasing pathological grade,TCT positive rate increased gradually,there was a correlation between them(r =0.629,P <0.05).With increasing pathological grade,HR -HPV positive rate increased gradually,there was a correlation between them(r =0.684,P <0.05).The sensitivity of HR -HPV combined with TCT in the differ-ential diagnosis of cervical cancer,precancerous lesions was 100.00%,specificity was 79.64%,missed diagnosis rate was 0.00%,the misdiagnosis rate was 20.36%.Conclusion HR -HPV combined with TCT examination has high clinical value in the diagnosis of cervical cancer and precancerous lesions.