Study on the clinical value of serum procalcitonin in early diagnosis of systemic bacterial infection
10.3760/cma.j.issn.1008-6706.2017.04.029
- VernacularTitle:血清降钙素原对全身细菌性感染的早期诊断价值研究
- Author:
Jun ZHANG
- Keywords:
Procalcitonin;
Bacterial infection;
Early diagnosis;
Clinical value
- From:
Chinese Journal of Primary Medicine and Pharmacy
2017;24(4):593-595
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the clinical value of serum procalcitonin(PCT)in early diagnosis of systemic bacterial infection.Methods 57 suspected bacterial infectious patients in our hospital were selected as observation group,and another 57 healthy subjects were selected as control group.Patients in the observation group were divided into sepsis group (A group,19 cases),local bacterial infection group (B group,19 cases)and bacterial infectious SIRS group (C group,19 cases)according to ACCP/SCCM consensus conference and their clinical manifestations. The serum PCT levels in the 4 groups were detected and compared.Results There was no statistically significant differences in general situation (age,sex,height,weight and body mass index (BMI),etc.)between the two groups (P >0.05).After admission,the PCT level in the observation group was obviously higher than that in the control group,the level of PCT was the highest in group A,and the difference was statistically significant(F =94.88,P <0.001).24h,3d,7d and 10d after admission,there was no statistically significant difference in PCT level in control group(P >0.05);the PCT level in the observation group was gradually decreased,the level of PCT in A group was still higher than that in the other three groups,and the differences were statistically significant(F =62.40,P <0.001;F =65.00,P <0.001;F =58.84,P <0.001;F =63.05,P <0.001).Conclusion Serum PCT has a certain advan-tage in sensitivity and specificity,it can reflect the severity of disease,it also has certain clinical significance in judging the development and prognosis of disease.Therefore,it can be considered as one of the first choice for clinical detection of bacterial infection.
