The gene polymorphism study of Mycobacterium tuberculosis in the drug-resistance surveillance and epidemi-ological survey field
10.3760/cma.j.issn.1008-6706.2017.04.037
- VernacularTitle:结核分枝杆菌基因多态性研究在耐药监测和流行病学调查中的应用
- Author:
Na ZHAO
;
Jinxia LIU
;
Dianxing SUN
- Keywords:
Extensively drug-Resistant tuberculosis;
Epidemiologic studies;
Mycobacterium tuberculo-sis;
Genomic structural variation
- From:
Chinese Journal of Primary Medicine and Pharmacy
2017;24(4):620-625
- CountryChina
- Language:Chinese
-
Abstract:
Tuberculosis is a chronic infectious diseases caused by Mycobacterium tuberculosis(MTB).As the drug-resistance characteristics are different in patients with various genotypes,thus,the gene polymorphism study have critical clinical significance.Among the all kinds of techniques,some have been used to analyze polymorphism for a long time and new development in that respect has also been made recently.On the other hand,some techniques are e-merging but demonstrate promising application prospects.This study summarizes the gene polymorphism study of MTB which have been used or are emerging in recent years,and points out a few shortcomings briefly.Our object is to make a contribution to theoretical basis and knowledge accumulation in the drug-resistance and epidemiological survey field.
