Outcome of modified intracytoplasmic sperm injection using zona pellucida -bound spermatozoa in male ;infertility
10.3760/cma.j.issn.1008-6706.2017.02.011
- VernacularTitle:卵透明带结合法筛选精子在男性不育症卵胞浆内单精子注射治疗中的应用
- Author:
Chaoqiang LI
;
Kaixin ZHU
;
Huiying HUANG
;
Lanqing FENG
;
Haizhu MAI
;
Yamin WU
;
Chunrong WU
- Keywords:
Spermatozoa;
Zona pellucida;
Intracytoplasmic sperm injection;
Embryo culture techniques
- From:
Chinese Journal of Primary Medicine and Pharmacy
2017;24(2):201-204
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the treatment outcome of modified intracytoplasmic sperm injection (ICSI)using zona pellucida(ZP)-bound sperm.Methods 82 patients with less,weak,abnormal sperm disease who were conformed to ICSI,were divided into traditional ICSI group and the group of modified ICSI using ZP-bound sperm according to ICSI case number.The results of normal fertilization rate,cleavage rate,high-quality embryo rate, planting rate,clinical pregnancy rate and early abortion rate were compared.Results The women's age,the sterility year,mature egg rate,normal fertilization rate,cleavage rate in the two groups had no statistically significant differ-ences (all P>0.05).The planting rate and clinical pregnancy rate of the observation group (46.6%,63.3%)were higher than those of the control group(38.5%,53.6%),but there were no statistically significant differences(all P>0.05).The using embryo rate and high-quality embryo rate of the observation group (73.9%,51.0%)were signifi-cantly higher than those of control group(65.8%,38.6%),the differences were statistically significant(χ2 =5.84,χ2 =11.6,all P<0.05).Conclusion Modified ICSI using ZP-bound sperm can effectively improve the embryos quality in ICSI.
