Update on the pathogenesis of diabetic nephropathy
10.3760/cma.j.jssn.1673-4904.2016.12.023
- VernacularTitle:糖尿病肾病发病机制研究进展
- Author:
Kexin FENG
;
Genyang CHENG
;
Luling YANG
;
Xianqing YIN
- Keywords:
Diabetic nephropathy;
Pathogenesis;
Therapy;
Review
- From:
Chinese Journal of Postgraduates of Medicine
2016;39(12):1134-1137
- CountryChina
- Language:Chinese
-
Abstract:
Diabetic nephropathy is a complication of diabete and its incidence is increasing obviously these years. The pathogenic mechanisms of DN are complex, with multiple factors involved such as the glycometabolism disorders , hemodynamic changes, aldose reductase pathway activation, alterations in cytokines, oxidative stress, protein kinase C activation, lipid metabolism disorders and genetic susceptibility etc, which are not completely clear yet. Thus, the research progress of DN pathogenesis is to be reviewed.
