Comparison of the effect of different surgical procedures on ovarian reserve and analgesic effects of drug use ;in patients with uterine fibroids
10.3760/cma.j.issn.1008-6706.2017.02.023
- VernacularTitle:不同术式对子宫肌瘤患者卵巢储备功能及镇痛药物应用效果影响的比较
- Author:
Jingyue MAO
;
Rui LIU
;
Caiyun LI
- Keywords:
Uterine fibroids;
Ovarian function tests;
Analgesia
- From:
Chinese Journal of Primary Medicine and Pharmacy
2017;24(2):247-251
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the impact of different surgical procedures on ovarian reserve and analge-sic effects of drug use in patients with uterine fibroids.Methods 100 patients with uterine fibroids were randomly divided into two groups.50 patients in control group were implemented traditional open surgery.50 cases in the obser-vation group received laparoscopic myomectomy.The ovarian reserve changes were compared before and after surgery, pain medication use and changes in the degree of pain conditions.Results The levels of follicle stimulating hormone and luteinizing in the control group one,three months after operation were significantly higher than before surgery and the observation group,the level of estrogen was significantly lower than before surgery and observation group,the differences were statistically significant(t=10.23,14.58,9.78,11.76,9.83,9.92,10.07,11.23,all P<0.05).The postoperative first pain time of the observation group was significantly longer than the control group,the difference was statistically significant[(513.74 ±284.52)min vs.(61.38 ±37.21)min,t=92.34,P<0.05].The postoperative analgesic usage of the observation group was significantly lower than the control group,the difference was statistically significant(14.0% vs.58.0%,χ2 =7.83,P<0.05).The pain scores 3d,4d,5d,6d and 7d after operation of the observation group were significantly lower than the control group(t=2.11,2.30,2.58,7.03,6.46,all P<0.05). Conclusion The patients with uterine fibroids laparoscopic myomectomy for treatment will not cause great impact on the patients'ovarian reserve,and can effectively reduce the use of analgesics,and it is worthy of further promotion.
