Relationship between ANXA1 and recurrence and metastasis of malignant tumors
10.3760/cma.j.issn.1008-6706.2017.02.039
- VernacularTitle:膜联蛋白Ⅰ与恶性肿瘤复发转移的关系
- Author:
Caiping SUN
;
Liming HUANG
;
Chaoyang XU
;
Jianfang WANG
- Keywords:
Malignant neoplasm;
Prognosis;
Metastasis;
ANXA1
- From:
Chinese Journal of Primary Medicine and Pharmacy
2017;24(2):307-309
- CountryChina
- Language:Chinese
-
Abstract:
Malignant neoplasm recurrence is the most important prognostic factor for patients.Looking for tar-get gene is an important part of cancer research.Annexin Ⅰ (ANXA1 )is to be discovered in the seventies century, composition by 13 calcium -phospholipid binding proteins annexin superfamily members of the first molecules. ANXA1 expressed in a variety of malignant tumors,ANXA1 expression levels were significantly reduced or absent in most tumor tissues.The study found that changed ANXA1 expression in tumor cells may have a causal relationship with the malignant phenotype of tumor cells.This paper aims to investigate the relationship between annexin Ⅰ and malignant neoplasm metastasis.
