Antiplatelet therapies in ischemic stroke patients with diabetes mellitus or insulin resistance
10.3760/cma.j.issn.1673-4165.2016.10.013
- VernacularTitle:合并糖尿病或胰岛素抵抗的缺血性卒中患者的抗血小板治疗
- Author:
Zhenguang LI
;
Tong WANG
;
Jinbiao ZHANG
;
Xinghua CUI
;
Jiangshan ZHANG
- Keywords:
Stroke;
Brain Ischemia;
Diabetes Mellitus,Type 2;
Insulin Resistance;
Blood Platelets;
Platelet Aggregation Inhibitors
- From:
International Journal of Cerebrovascular Diseases
2016;24(10):930-935
- CountryChina
- Language:Chinese
-
Abstract:
Diabetes mellitus is an independent predictor of high platelet reactivity after antiplatelet therapy in patients with ischemic stroke,and the latter is closely related to the increased risk of recurrence of stroke.The mechanisms of high platelet reactivity in patients with diabetes or insulin resistance are associated with a variety of factors.Some circulating molecules can be used as markers for predicting the reactivity of platelets.Monitoring of platelet reactivity after treatment with new antiplatelet agents may provide basis for individualized antithrombotic therapy in ischemic stroke patients with diabetes or insulin resistance.
