Risk factors for symptomatic intracranial hemorrhage after intravenous thrombolysis in patients with acute ischemic stroke
10.3760/cma.j.issn.1673-4165.2016.10.012
- VernacularTitle:急性缺血性卒中患者静脉溶栓后有症状颅内出血的危险因素
- Author:
Mingyong LIU
;
Yongjun WANG
- Keywords:
Stroke;
Brain Ischemia;
Intracranial Hemorrhages;
Thrombolytic Therapy;
Risk Factors
- From:
International Journal of Cerebrovascular Diseases
2016;24(10):924-929
- CountryChina
- Language:Chinese
-
Abstract:
Intravenous thrombolysis has been proved as an effective therapy for acute ischemic stroke.However,symptomatic intracranial hemorrhage (sICH) occurred after thrombolysis will affect the recovery of patients,even endangers life when it is serious.Therefore,determining the risk factors for sICH after thrombolysis is helpful to select appropriate patients for thrombolytic therapy.The risk factors for slCH after thrombolysis include advanced age,male gender,obesity,higher National Institutes of Health Stroke Scale scores,hypertension,diabetes or higher blood glucose,atrial fibrillation,delayed thrombolysis time,antiplatelet therapy,anticoagulation therapy,and leukoaraiosis.However,some of the risk factors still have conflicting reports.Further large sample clinical studies are needed to confirm them.