Exosomes and leukemia
10.3760/cma.j.issn.1673-4408.2017.01.009
- VernacularTitle:外泌体与白血病
- Author:
Xiumin REN
- Keywords:
Exosomes;
Leukemia
- From:
International Journal of Pediatrics
2017;44(1):36-39
- CountryChina
- Language:Chinese
-
Abstract:
Exosome is a type of nanosized membrane microvesicle that contains bioactive constituents and signal molecules.Exosomes have been shown to be released by the cells in vivo.Leukemia cell-derived exosomes were found in the plasma of leukemia patients and supernatant of leukemia cells after centrifuge.Leukemia cell-derived exosomes and Technology Development Program of Medicine can transfer leukemia-associated antigens and mieroRNA to target cells.Not only does it affect the development of leukemia,but it is also closely related to the treatment and prognosis of leukemia.
