Experimental Study on Antitussive, Expectorant and Antiasthmatic Effects of Fortunella Hindsii Leaves
- VernacularTitle:山橘叶镇咳祛痰平喘作用的实验研究
- Author:
Jian ZOU
;
Wei WANG
;
Jie LI
- Keywords:
Leaf of Fortunella hindsii;
Antitussive;
Expectorant;
Antiasthmatic
- From:
China Pharmacist
2017;20(2):256-258
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To study the antitussive, expectorant and antiasthetic effects of Fortunella hindsii leaves. Methods: The antitussive effects were observed by the method of ammonia-induced cough in mice, the expectorant effects were observed by the method of phenolsulfonphthalein excretion in mice, and the antiasthmatic effects were observed by the method of histamine phosphate spray in guinea pigs. Results:The leaves of Fortunella hindsii at low, medium and high doses could decrease the cough times and prolong the cough latent period (P<0. 05 or P<0. 01), high dose could promote the phenol red excretion (P<0. 05), and high and medium do-ses could prolong the incubation period of guinea pigs for asthma caused by histamine phosphate (P<0. 05 or P<0. 01). Conclu-sion:The leaves of Fortunella hindsii have promising antitussive, expectorant and antiasthmatic effects.
