Extraction Technology Optimization for Tetrahydropalmatine from Corydalis Yanhusuo by Orthogonal Ex-periment
- VernacularTitle:正交试验法优选延胡索中延胡索乙素提取工艺
- Author:
Bo YANG
;
Hongyu JI
;
Linhua WU
;
Yiping ZHENG
;
Liping SHEN
;
Dongyou ZHENG
- Keywords:
Corydalis yanhusuo;
Tetrahydropalmatine;
HPLC;
Orthogonal experiment;
Extraction technology
- From:
China Pharmacist
2017;20(2):273-276
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To optimize the extraction technology of tetrahydropalmatine in Corydalis yanhusuo. Methods:An L9 (34 ) orthogonal experiment was performed to investigate the effects of ethanol concentration, ethanol amount, extraction temperature and ex-traction time on the extraction results with the content of tetrahydropalmatine as the evaluation index. Results:The optimum conditions were as follows:the solid-liquid ratio was 1 :10 ( g·ml-1 ) , 60% ethanol was used as the extraction solvent, the extraction tempera-ture was at 80 ° C for three-time extraction, and the extraction duration for each time was 1 h. Conclusion: The optimized extraction technology for tetrahydropalmatine from Corydalis yanhusuo is stable, reasonable, feasible and easy-operated with low energy consump-tion, which can enhance the comprehensive utilization of Corydalis yanhusuo.
