Clinical Efficacy and Effects on Hemorheology of Acupuncture Therapy Combined with Gabapentin in the Treatment of Patients with Tension Headache
- VernacularTitle:针刺联合加巴喷丁治疗紧张性头痛患者的疗效及对血液流变学的影响观察
- Author:
Jun ZHU
;
Xinrong YE
;
Zhiqing ZHUANG
;
Weixia GU
;
Molan WANG
- Keywords:
Acupuncture therapy;
Gabapentin;
Tension headache;
Efficacy;
Hemorheology
- From:
China Pharmacist
2017;20(2):290-292
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the clinical efficacy and effects on hemorheology of acupuncture therapy combined with gaba-pentin in the treatment of patients with tension headache. Methods:Totally 92 cases of patients with tension headache were randomly divided into the observation group (n=46) and the control group (n=46) according to the random number table. The control group was given gabapentin, while the observation group was treated with acupuncture therapy on the basis of treatment in the control group. The treatment course was 4 weeks. The clinical efficacy, changes of the headache indices, VAS score and hemorheology levels before and after the treatments in the two groups were compared, and the incidence of adverse reactions was observed as well. Results:The to-tal effective rate of the observation group (93. 48%) was significantly higher than that of the control group (73. 91%, P<0. 05). Af-ter the treatment, the headache indices in both groups significantly decreased (P<0. 05), and the decrease in the observation group was more significant than that in the control group (P<0. 05). The VAS scores in both groups significantly decreased after the treat-ment (P<0. 05), and the decrease in the observation group was more significant than that in the control group (P<0. 05). The plas-ma viscosity, hematocrit and platelet aggregation rate in both groups significantly decreased after the treatment (P<0. 05), and the decrease in the observation group was more notable than that in the control group (P<0. 05). No severe adverse reactions were shown in both groups during the treatment course. Conclusion: Acupuncture therapy combined with gabapentin in the treatment of patients with tension headache shows striking effects, which can improve hemorheology with promising safety and deserves further studies.
