Research progress of mechanisms outer membrane proteins of Helicobacter pylori and its adherence
10.3969/j.issn.1674-8115.2017.02.024
- VernacularTitle:幽门螺杆菌外膜蛋白与黏附机制的研究进展
- Author:
Qiaoyun ZHAO
;
Yong XIE
- Keywords:
Helicobacter pylori;
outer membrane proteins;
adherence;
vaccine
- From:
Journal of Shanghai Jiaotong University(Medical Science)
2017;37(2):249-252
- CountryChina
- Language:Chinese
-
Abstract:
Helicobacter pylori is a predominant pathogen inducing long-term chronic infection of stomach. Its outer membrane proteins (OMPs) mainly include lipoprotein, fimbriae protein and some adhesions. The adhesions are closely related to the pathogenic processes of adherence, colonization, persistent infection and severe clinical outcomes. In addition, the fact that adherence is vital for colonization and pathogenicity has made it a focus to study the vaccines against adherence. The OMPs related to adherence, their receptors, mechanisms of adherence, and the vaccines are summarized in this review.
