Clinical Evaluation on Improving Living Quality of Patients with Yang-deficiency of Spleen and Kidney of Premature Ovarian Failure with Modified Yulin Decoction Based on SF-36 Scale
10.3969/j.issn.1005-5304.2017.03.007
- VernacularTitle:基于SF-36量表的加减毓麟汤改善卵巢早衰脾肾阳虚证患者生活质量临床评价
- Author:
Xiuxiang TENG
;
Peipei LI
;
Haiyang YAO
;
Jingjing YUAN
- Keywords:
premature ovarian failure;
yang-deficiency of the spleen and kidney;
modified Yulin Decoction;
living quality;
SF-36 scale
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2017;24(3):26-29
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the effect of the modified Yulin Decoction on improving the living quality of patients with yang-deficiency of the spleen and kidney of premature ovarian failure. Methods One hundred and twenty-seven patients were divided into experimental group (80) and control group (47) by non-randomized noninferiority comparative study. The experimental group was treated with modified Yulin Decoction daily orally once a day. The control group was treated with oral estradiol valerate and progesterone cycle. Two groups received continuous medication for 21 d, and treatment interval was 5 d. Three cycles of treatment were set as one course, and treated for 2 courses. The SF-36 scale was used to calculate the total scores and scores of eight dimensions before and after treatment. Results Before treatment, there was no significant difference (P>0.05) in the scores of SF-36 dimensions (except somatic pain) and total score between the two groups. Compared with before treatment, the score and total score of SF-36 in the experimental group increased (P<0.05, P<0.01). The mental health score of the control group was higher than that of before treatment (P<0.05, P<0.01). After treatment, there was statistical significance in the two dimensions of vitality and mental health in the two groups (P<0.05). There were significant differences (P<0.01) in the total score and scores of SF-36 physiological function, physical pain, general health, vigor, social function, emotional function and mental health between the two groups. Conclusion Modified Yulin Decoction can improve the living quality of patients with yang-deficiency of the spleen and kidney of premature ovarian failure.