Research progress of the role of thrombin activatiable fibrinolysis inhibitor in cardiovascular and cerebrovascular diseases
- VernacularTitle:凝血酶激活的纤溶抑制物在心脑血管疾病中作用的研究进展
- Author:
Yingjie LI
;
Baoxue YANG
- Keywords:
thrombin activation of fibrinolysis inhibitor;
cerebral thrombosis;
cardiovascular diseases
- From:
Basic & Clinical Medicine
2017;37(2):261-264
- CountryChina
- Language:Chinese
-
Abstract:
Thrombin activated fibrinolysis inhibitor ( TAFI) is a kind of plasma enzymes that can be activated by thrombin.TAFI regulates blood coagulation and fibrinolysis and has a strong fibrinolytic and anti-inflammatory ac-tivity.Its inhibitor is expected to minimize the risk of bleeding when thrombolytic recanalization .Also, studies found that TAFI played an important role in the development of cerebral thrombosis;atherosclerosis and so on .