Effect of duration of subcutaneous injection on the extent of bruising at injection sites among patients receiving low-molecular weight heparin:a Meta-analysis
10.3760/cma.j.issn.1672-7088.2017.02.019
- VernacularTitle:低分子肝素皮下注射推注时间对注射部位皮下出血影响的Meta分析
- Author:
Ruihong ZHANG
;
Chunlei LIU
;
Jixian WU
- Keywords:
Heparin,low-molecular-weight;
Injections,subcutaneous;
Hemorrhage;
Meta-analysis
- From:
Chinese Journal of Practical Nursing
2017;33(2):152-156
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the effect of duration of subcutaneous injection on the extent of bruising at injection sites among patients receiving low- molecular weight heparin. Methods Randomized clinical trials and quasi-experimental within-subject design that assessed the effect of subcutaneous duration on the bruising of injection sites were selected in Cochrane library, JBI evidence-based practice medical and nursing database, PubMed biomedical information retrieval platform, Medline general medical literature retrieval database. RevMan5.3 software was used to analyze the data after quality assessment, and data extraction were made for eligible trials. Results A total of 9 trials were included. The results of Meta-analysis supported the 30 s duration injection technique on reducing the rate of bruising of injection sites than 10 s duration injection technique (odds ratio was 0.34,95%confidence interval 0.25-0.47, P<0.01).While it was failed to support the effect on reducing the bruising area 48 and 72 hours after injection (P > 0.05). Conclusions Increasing the length of low-molecular weight heparin subcutaneous injection can reduce the rate of bruising. While it could not effectively reduce the area.
