Effect of sperm spreparation in male infertility on sperm morphology and DNA integrity
10.3969/j.issn.1006-5725.2017.02.017
- VernacularTitle:优化处理技术对男性不育症患者精子形态和DNA碎片指数的影响
- Author:
Yichun ZHENG
;
Liqing XU
;
Jiaying LIANG
;
Ting TANG
;
Lihu WANG
;
Fenghua LIU
- Keywords:
Male infertility;
Sperm process;
Sperm morphology;
DNA fragmentation index
- From:
The Journal of Practical Medicine
2017;33(2):231-234
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of sperm preparation in male infertility on sperm morphology and DNA fragmentation index(DFI). Methods Four hundred men were divided into the groups of fertile , teratozoospermics and unexplained subfertility. Sperm morphology and DFI were analyzed before and after the sperm preparation. Results Sperm abnormal morphology and DFI in the infertility group were higher than those in the fertile group ,but significantly decreased after sperm preparation. The method of density gradient separation results in obtaining better sperm(P<0.01). Conclusions Compared to the method of swimming up ,the method of density gradient separation could result in obtaining sperm with improved normal morphology and DNA integrity.
