Relationship between the Red Cell Volume Distribution Width in Patients with Gestational Diabetes and Insulin Resistance
10.3969/j.issn.1671-7414.2017.01.018
- VernacularTitle:妊娠期糖尿病患者红细胞分布宽度与胰岛素抵抗的相关性研究
- Author:
Fei GAO
;
Hongling YANG
;
Jielin WANG
;
Xiurong GAO
;
Yan LONG
;
Hao ZHENG
;
Xiaojuan CHEN
- Keywords:
gestational diabetes mellitus;
red cell volume distribution width;
insulin resistance
- From:
Journal of Modern Laboratory Medicine
2017;32(1):66-68
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the relationship between the red cell volume distribution width (RDW)in patients with ges-tational diabetes and insulin resistance(IR).Methods A total number of 160 pregnancies performed in Guangzhou Women and Children’s Medical Center from January to October 2016.Matching 80 patients with gestational diabetes (the GDM Group)with 80 healthy pregnancies according to their age,gestational weeks and times.Their inflammatory parameters (hs-CRP,neutrophil-to-lymphocyte ratio,RDW)were respectively examined.HOMA-IR was calculated by testing the level of FBG and FIns.The association of the red cell volume distribution width with insulin resistance was analyzed.Results The level of four inflammatory parameters (hs-CRP,WBC,neutrophil-to-lymphocyte ratio,RDW)were significantly higher than that the control group (t=5.695,5.232,3.337,7.814,all P<0.01).Pearson correlated analysis suggested that RDW had positive correlation with HOMA-IR (r=0.58,P<0.01).Conclusion The RDW level were elevated in the GDM patients and had positive correlation with HOMA-IR,which indicated that IR was associated with inflammation and provided proof to research mechanism of GDM.
