Progress on the Study and Application of Serum Adenosine Deaminase in the Diagnosis of Autoimmune Diseases
10.3969/j.issn.1671-7414.2017.01.045
- VernacularTitle:血清腺苷脱氨酶检测在自身免疫性疾病诊断中的应用价值研究进展
- Author:
Guanhua ZHAO
;
Zhaowei GAO
;
Huizhong ZHANG
- Keywords:
adenosine deaminase(ADA);
autoimmune disease(AID);
isoenzyme
- From:
Journal of Modern Laboratory Medicine
2017;32(1):160-164
- CountryChina
- Language:Chinese
-
Abstract:
Adenosine deaminase (ADA)plays an important role in the regulation of normal immune system.The altered activ-ity of serum ADA could associate with some autoimmune diseases(AID).Various studies abroad have found the elevated ac-tivity of serum ADA compared with healthy controls in many kinds of AID such as systemic lupus erythematosus (SLE), rheumatoid arthritis(RA),et al (P<0.05).Many studies foused on the correlation of altered activity of serum ADA with the disease severity,but there is still controversy.To explore the diagnostic value of serum ADA in AID,make a review a-bout the application research progress of ADA in several AID.
