Comparative analysis of effective dose between helical tomotherapy and multi-ISO radiotherapy in craniospinal irradiation
10.3760/cma.j.issn.0254-5098.2017.01.009
- VernacularTitle:两种全中枢神经系统放疗技术患者有效剂量的比较
- Author:
Xiongfei LIAO
;
Churong LI
;
Jie LI
;
Yazheng CHEN
;
Ke YUAN
;
Pei WANG
- Keywords:
Craniospinal irradiation;
Helical tomotherapy;
Multi-ISO radiotherapy;
Effective dose
- From:
Chinese Journal of Radiological Medicine and Protection
2017;37(1):45-49
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the effective dose deposited in patients between helical tomotherapy (HT) and multi-ISO radiotherapy (M-ISO) in carniospinal irradiation (CSI).Methods Nine children with craniospinal irradiation were selected .For these patients , new plans were designed with HT and M-ISO centers planning method on the treatment planning system ( TPS) .The effective dose of the nine patients from 18 treatment plans were calculated ,and the difference of the effective dose between HT and M-ISO was compared using paired t-test.Results The plans designed in two groups were both satisfied all clinical requirements .For the planning target volume ( PTV ) , no statistically significant difference was found in D95% between two groups ( P>0.05 ) , while D98%, D2% and homogeneity index (HI) in HT group were superior to M-ISO group (t=2.762, 2.413, 4.563, P<0.05), D50%, Dmean and CI in M-ISO group were superior to HT group (t=5.259, 3.685, 7.815, P<0.05).HT and M-ISO had different advantages in the protection of the OARs .The effective dose of patients in M-ISO group was superior to HT group (t=5.921, P<0.05).Conclusions HT and M-ISO have different advantages in CSI.The low dose area has greater influence on the effective dose in HT group compared to M-ISO group. The low dose area should be concerned while designing the treatment planning for CSI .
