The research progress for anti-tumor strategies of radiotherapy and immunotherapy
10.3760/cma.j.issn.0254-5098.2017.01.014
- VernacularTitle:放疗联合免疫抗肿瘤治疗策略的研究进展
- Author:
Liu YANG
;
Xiling ZHU
;
Gong LI
- Keywords:
Immunotherapy;
Radiotherapy;
Tumor;
Strategies
- From:
Chinese Journal of Radiological Medicine and Protection
2017;37(1):73-77
- CountryChina
- Language:Chinese
-
Abstract:
With the deeper understanding of tumor , more and more evidence indicates that the occurrence and development of tumors are closely related to the body′s immune function .More and more researches focus on tumor immunology to find an effective way of enhancing anti-tumor immunity . Radiotherapy has played an important role in anti-tumor immunity recently though it was believed as a traditional treatment for cancer before .Radiotherapy could convert a cold tumor into a hot tumor, which might ameliorate immune suppressive microenvironment , improve tumor immunogenicity and activate the cellular immune response .However, the abscopal effectof single radiotherapy is very rare . Immunotherapy is capable of enhancing the immune response produced by radiotherapy .In this paper , the basic theory and clinical practice of radiotherapy and immunotherapy were reviewed and the related clinical strategies were summarized .
