Study on the correlation of SIRT3 with metabolic syndrome and myocardial hypertrophy
10.3760/cma.j.issn.1000-6699.2017.01.014
- VernacularTitle:SIRT3基因与代谢综合征及心肌肥厚的相关性研究
- Author:
Yanyan MA
;
Huiping GONG
;
Lin ZHU
;
Yimeng DU
;
Yinwang ELOY
- Keywords:
Sirtuin family;
SIRT3;
Metabolic syndrome;
Cardiac hypertrophy
- From:
Chinese Journal of Endocrinology and Metabolism
2017;33(1):75-77
- CountryChina
- Language:Chinese
-
Abstract:
[Summary] SIRT3 is a member of the silent information regulator 2 ( Sir2) family, located in the inner mitochondrial membrane, with a strong effect of deacetylation. SIRT3 not only modulates energy metabolism, cell apoptosis, tumor growth, anti-aging etc. , but also plays an important role in the field of cardiovascular diseases. In this review, we summarize recent findings related to SIRT3 with metabolic syndrome and cardiac hypertrophy, to provide a theoretical basis for the further study on the potential role of SIRT3 in cardiovascular diseases.
