Research of serum microRNA in diagnose of hepatocellular carcinoma
10.3760/cma.j.issn.1009-9158.2017.01.016
- VernacularTitle:血清微小RNA在肝癌诊断的应用进展
- Author:
Jia HE
;
Bin XIAO
;
Zhaohui SUN
- Keywords:
Liver neoplasms;
Carcinoma,hepatocellular;
MicroRNAs;
Biological markers
- From:
Chinese Journal of Laboratory Medicine
2017;40(1):72-76
- CountryChina
- Language:Chinese
-
Abstract:
MicroRNAs ( miRNAs) , which are endogenous small noncoding RNAs , mainly regulate the expression of many target genes at the post-transcriptional and ( or ) translational levels.Aberrant expressions of several miRNAs were found in a large variety of neoplasms , including hepatocellular carcinoma ( HCC).Previous studies have shown the existence of a large amount of stable miRNAs in human serum, which have laid the foundation for studying the role of serum miRNAs in the diagnosis and prognosis of HCC.
