Advances in rabbit models of cardiac arrest-cardiopulmonary resuscitation
10.3760/cma.j.issn.2095-4352.2016.12.021
- VernacularTitle:家兔心搏骤停-心肺复苏模型研究进展
- Author:
Menyuan DIAO
;
Jun GUAN
;
Zhaofen LIN
;
Zhe ZHANG
;
Yan XIAO
- Keywords:
Cardiac arrest;
Cardiopulmonary resuscitation;
Rabbits;
Animal models
- From:
Chinese Critical Care Medicine
2016;28(12):1157-1160
- CountryChina
- Language:Chinese
-
Abstract:
The successful establishment of animal models of cardiac arrest-cardiopulmonary resuscitation (CA-CPR) undoubtedly provided an important basis for exploring the method of cardiopulmonary resuscitation (CPR) and advanced cardiovascular life support (ACLS). However, pathophysiology varied with the etiology of cardiac arrest (CA). Therefore, preparation of similar animal models according to etiology was the basis for pathophysiological changes research. Compared with other animals, the rabbits had both the advantages of large and small animals, so they became common research object for the CA-CPR model. This paper reviewed the common methods of animal models of CA-CPR in rabbits. In this review, the methods, criteria, advantages, disadvantages and precautions of each model were analyzed, which would provide useful reference for CPR researchers.
