Progress in association between autophagy and cancer
10.11904/j.issn.1002-3070.2016.06.013
- VernacularTitle:细胞自噬与肿瘤关系的研究进展
- Author:
Tingting REN
;
Ying XING
;
Qingwei MENG
- Keywords:
Autophagy;
Tumor;
Chemotherapy drug resistance
- From:
Practical Oncology Journal
2016;30(6):543-546
- CountryChina
- Language:Chinese
-
Abstract:
Autophagy is a highly conservative biological behavior in eukaryotic cells .This dynamic process involves wrappingcytoplasmic components and combining with lysosomes in cells for catabolism .Auto-phagy can not only take part in maintaining homeostasis ,but also be closely related with tumor development and resistant.Therefore,autophagy is a potential target for antitumor drug resistant .Specific inhibition of autophagy in cancer cells combined with chemotherapy is expected to be an effective cancer treatment strategy .
