Progress in the research of CyclinD1 in urinary tumor
10.11904/j.issn.1002-3070.2016.03.014
- VernacularTitle:CyclinD1表达与泌尿系统肿瘤关系的研究进展
- Author:
Defang NIU
;
Yan CUI
;
Hui CHEN
- Keywords:
CyclinD1;
Urothelial carcinoma;
Renal carcinoma;
Prostatic carcinoma;
Penile carcinoma
- From:
Practical Oncology Journal
2016;30(6):547-550
- CountryChina
- Language:Chinese
-
Abstract:
Cyclin D is the most closely relationship with tumor ,and it is currently known one of the sub-types of cyclins.CyclinD1,as a positive regulatory factor ,has an important role in the process of cell cycle ,espe-cially in cell proliferation and division .CyclinD1 is unusually up-regulated in lots of human cancers .CyclinD1 is a recently discovered protein which is highly expressed in the urinary tumors ,and its expression in tumors is asso-ciated with a more aggressive phenotype ,prognosis and recurrence .Therefore,the research of the target point to CyclinD1 in the urinary tumors may provide a new method for the therapy to urinary tumors .
