Role of Microglia Autophagy in Ischemic Stroke (review)
10.3969/j.issn.1006-9771.2016.12.011
- VernacularTitle:小胶质细胞自噬在缺血性脑卒中中作用的研究进展
- Author:
Dong WANG
;
Boru HOU
;
Wenzhen YANG
;
Junlin KANG
;
Haijun REN
- Keywords:
ischemic stroke;
microglia;
autophagy;
review
- From:
Chinese Journal of Rehabilitation Theory and Practice
2016;22(12):1416-1419
- CountryChina
- Language:Chinese
-
Abstract:
Autophagy plays an important role in the regulation of activation and inflammation of microglia after ischemic stroke. The interaction between autophagy of microglia and the inflammation mediated by microglia after ischemic stroke was complex and a large num-ber of molecules were involved. The receptors of microglia activation and related substances may be possible mechanism in the regulation of microglia autophagy. Autophagy inhibitors and microglia receptor targeting therapy may provide new strategies for the clinical treatment of ischemic stroke. This paper summarized the progress of microglia autophagy after ischemic stroke.
