Level of Serum Vascular Endothelial Growth Factor in Patients with Cerebral Infarction before and after Rehabilitation

VernacularTitle:脑梗死患者康复治疗前后血管内皮生长因子水平的比较
Author: Liping LU ; Dechun SANG ; Fan BAI ; Hui CHEN ; Fan YANG ; Hongyu CHU ; Xiaoyu ZHANG ; Xin LI ; Jianhua LIU
Publication Type:Journal Article
Keywords: vascular endothelial growth factor; cerebral infarction; rehabilitation; vascular regeneration
From: Chinese Journal of Rehabilitation Theory and Practice 2016;22(12):1434-1437
CountryChina
Language:Chinese
Abstract: Objective To investigate the change of serum vascular endothelial growth factor (VEGF) in cerebral infarction before and af-ter rehabilitation. Methods Forty-eight patients with first cerebral infarction were enrolled from June, 2014 to August, 2016 in Beijing Bo'ai Hospital. Level of serum VEGF was measured by enzyme-linked immunosorbent assay (ELISA) before and six weeks after rehabilitation. The level of serum VEGF of 33 normal subjects was compared with the patients'. Results The level of serum VEGF was higher in the pa-tients group than in the control group before and six weeks after rehabilitation (t>2.540, P<0.05). The level of VEGF was higher in the large area infarction group (>4 cm) than in the small area infarction group (≤4 cm) (t=4.436, P<0.05), and was higher in the short course (less than one month) infarction group than in the long course (more than one month) group (t=2.316, P<0.05). Conclusion VEGF can be main-tained in high level after rehabilitation.