Progress in mitochondrial fusion, fission and inflammatory response
10.3969/j.issn.1000-4718.2016.12.030
- VernacularTitle:线粒体的融合、分裂与炎症反应研究进展
- Author:
Xiangyun LI
;
Jianbo YU
- Keywords:
Mitochondrial dynamics;
Inflammatory response;
Inflammatory mediators
- From:
Chinese Journal of Pathophysiology
2016;32(12):2295-2299
- CountryChina
- Language:Chinese
-
Abstract:
The dynamism and health of the mitochondrial network are regulated by fission and fusion proteins , which help to maintain organelle vitality and the physiological state of the cell .Recently, accumulated evidence has demon-strated that the changes of mitochondrial dynamics have a great effect on inflammation in a variety of diseases .To the con-trary , inflammatory mediators regulate mitochondrial dynamics at the same time .The aim of this reviews is to summarize the relationship between them and to provide new clinical reference for preventing and curing diseases .