Effect of insulin sensitizer on endocrine disorder of patients with polycystic ovary syndrome
10.3969/j.issn.1005-1678.2016.11.032
- VernacularTitle:胰岛素增敏剂治疗多囊卵巢综合征内分泌紊乱患者的效果观察
- Author:
Xian CHEN
;
Ying LUO
- Keywords:
Polycystic ovary syndrome;
endocrine disorder;
insulin sensitivity
- From:
Chinese Journal of Biochemical Pharmaceutics
2016;36(11):109-111
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical effect of insulin therapy in the treatment of patients with polycystic ovary syndrome .Methods 91 cases of endocrine disorders of patients with polycystic ovary syndrome were selected from September 2013 to September 2016 in Yinzhou Ningbo people’s hospital,and divided into observation group and control group,44 cases in the control group and received conventional treatment,47 cases in the observation group and received insulin sensitizer on the basis of conventional treatment.Before and after treatment, the level of sex hormones, blood glucose and insulin levels in the two groups were detected and compared,and the efficacy was determined and compared.Results Compared with before treatment,the levels of LH,FSH,E2,T,A2,Ds in the observation group were decreased,SHBG was increased,HOMA-β,HOMA-IR,FPG,FINS were decreased,the difference was statistically significant (P<0.05);compared with control group, the levels of LH,FSH,E2,T,A2,Ds in the observation group were lower,SHBG was higher,HOMA-β,HOMA-IR,FPG,FINS were lower,the difference was statistically significant (P<0.05);After treatment, the total effective rate of observation group 95.74%was significantly higher than the control group 81.82%(P<0.05).Conclusion Insulin sensitizer in treatment of polycystic ovary syndrome in patients with endocrine disorders has significantly effect,can significantly improve the patient’s sex hormone levels and blood glucose levels,adjust the patient’s insulin levels,improve the clinical treatment efficiency.
