The Effect of Indirect Gentle Moxibustion on Serum IL-1 and TNF-? Contents in Patients with Knee Osteoarthritis
10.13460/j.issn.1005-0957.2016.12.1459
- VernacularTitle:隔物温和灸对膝骨关节炎患者血清IL-1及TNF-?含量的影响
- Author:
Xiubin LI
;
Zhengxiang LI
;
Lixin WANG
- Keywords:
Acupuncture;
Osteoarthritis,knee;
IL-1;
TNF-?;
Moxa stick moxibustion;
Indirect moxibustion;
Medicinal cake-partitioned moxibustion;
Electroacupuncture
- From:
Shanghai Journal of Acupuncture and Moxibustion
2016;35(12):1459-1461
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of indirect gentle moxibustion on serum IL-1 and TNF-?contents in patients with knee osteoarthritis and explore the mechanism of its action. Method A randomized controlled trial was conducted according to the patient's condition. Besides acupuncture as basic treatment, the treatment group received indirect gentle moxibustion and the control group, thermotherapy plus cupping. Pre-treatment and post-treatment serum IL-1 and TNF-?contents and the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) scores were analyzed in the patients and compared between the two groups. Result There were statistically significant pre-/post-treatment differences in serum IL-1 and TNF-? contents and the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) score in the two groups (P<0.05). After treatment, serum IL-1 and TNF-?contents and the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) score were lower in the treatment group than in the control group. Conclusion Indirect gentle moxibustion can effectively decrease serum IL-1 and TNF-?contents in patients with knee osteoarthritis. That provides a certain molecular cytobiological and bio tissue engineering basis for the mechanism of its action in reducing inflammatory stimulation.
