Therapeutic effects of gargled astragalus water decoction as the adjuvant therapy on serum CD14, TNF-αand IL-8 levels in acute suppurative pulpitis
10.3969/j.issn.1005-1678.2016.11.041
- VernacularTitle:黄芪水煎剂含潄辅助治疗对化脓性牙髓炎患者血清CD14、TNF－α及IL－8水平的影响
- Author:
Guokang WANG
;
Yuezong SUN
- Keywords:
astragalus water decoction;
gargle;
acute suppurative pulpitis;
CD14;
TNF-α;
IL-8
- From:
Chinese Journal of Biochemical Pharmaceutics
2016;36(11):138-140
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the effect of the gargled astragalus water decoction as the adjuvant therapy on serum CD14, TNF-αand IL-8 levels in patients with acute suppurative pulpitis.Methods 42 patients who were diagnosed with acute suppurative pulpitis in our hospital were collected. All patients were randomly divided into experimental group and control group, 21 cases in each group.Patients in the control group received conventional therapy, while patients in the experimental group were given the additional adjuvant therapy that gargled with astragalus water decoction.After the treatment, the serum levels of CD14,TNF-αand IL-8 were detected in all patients.Results After treatment, the serum levels of CD14, TNF-αand IL-8 in the experimental group were statistically lower than control group ( P<0.05 ) .Conclusion The gargled with astragalus water decoction as the adjuvant therapy could significantly reduce the serum CD14,TNF-αand IL-8 levels in patients with acute suppurative pulpitis,and it could obviously relieve inflammation.
